You have to disable the header and footer by setting the values to 0pt.

\setuplayout
  [backspace=15mm,
   width=middle,
   topspace=15mm,
   height=middle,
   header=0pt,
   footer=0pt]

\showframe

\starttext
\input knuth
\stoptext

You can also use the fullpage module when you equal margins for your document.

\usemodule[fullpage][style={margin,empty},margin=15mm]

\showframe

\starttext
\input knuth
\stoptext

Wolfgang