Gerben Wierda schrieb am 04.07.2023 um 23:17:
After erasing the font cache and regenerating LM was doing it right again.

Helvetica did not, but maybe I made a mistake in

\definefontfamily
  [helvetica]
  [ss]
  [Helvetica]
  [tf=style:Regular,
   bf=style:Bold,
   it=style:Oblique,
   bi=style:Bold Oblique]

Does it work when you remove the manual assignments to tf, it, etc. or when you use lowercase names (without spaces), e.g. "bi=boldoblique" (or "bi=bolditalic").

Wolfgang