My bad!!
Here is a MWE

\definefontfeature[default][default][onum=yes]

\definefontfamily[Florys][serif][TeX Gyre Termes]
\definefontfamily[Florys][sans] [TeX Gyre Heros]
\definefontfamily[Florys][mono] [TeX Gyre Cursor][features=none]
\definefontfamily[Florys][math] [TeX Gyre Pagella Math]


\setupbodyfont[Florys,12pt]
\starttext
\input knuth
\stoptext

On Sat, Sep 23, 2017 at 2:29 AM, Floris van Manen <vm@klankschap.nl> wrote:

>
> On 23 Sep 2017, at 02:14, Floris van Manen <vm@klankschap.nl> wrote:
>
>
> On 23 Sep 2017, at 00:30, kaddour kardio <kaddourkardio@gmail.com> wrote:
>
> you should  remove the line containing *simplefont*, you don’t
> have to load it to get a proper import of fonts, besides the TeX Gyre
> super family is already available with the distribution, either standalone
> or the texlive distro
>
>
>
>
> So the answer is that the command has changed:
> http://wiki.contextgarden.net/simplefonts
>
> However, the commands have slightly changed:
> \setmainfont
> is now
> \definefontfamily [myfamily] [serif] [DejaVu]
> (and the same syntax to set the sans, mono and math font).
>
>
>
> That works, of course ;-)
>
> .F
>
>
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-- 
Dr YAHYAOUI Mohamed Kaddour, cardiologue.Clinique EL ABRAR.