I have the 2.13 version installed. Well, no worries I hope it doesn't 
happen. 

If I need to create another folder for a new .md document and see the issue 
again I guess I'll reply inside this discussion. 

Thanks for all the help!

El viernes, 28 de mayo de 2021 a las 11:27:45 UTC-5, John MacFarlane 
escribió:

>
> You're not expected to create them. Pandoc works fine without
> them. But if you did have them, it could be implicitly using
> a reference-doc defined there, so I wanted to rule that out.
>
> Well, I can't reproduce your issue or think of anything that
> could be causing it.
>
> Please use pandoc --version and be sure you're running the
> latest version (2.13).
>
> Julio Vera <avenz...-Re5JQEeQqe8AvxtiuMwx3w@public.gmane.org> writes:
>
> > I never created this folder ~/.pandoc or this one ~/.local/share/pandoc. 
> I 
> > made a quick google search and found that I was expected to create those 
> > directories, I never found the guidelines in the documentation tho. So 
> > answering your question, I don't have a reference.docx because I haven't 
> > created those directories.
> >
> > thank you
> >
> > El jueves, 27 de mayo de 2021 a las 16:16:27 UTC-5, John MacFarlane 
> > escribió:
> >
> >>
> >> Do you have a folder ~/.pandoc or ~/.local/share/pandoc that
> >> contains reference.docx?
> >>
> >> Julio Vera <avenz...-Re5JQEeQqe8AvxtiuMwx3w@public.gmane.org> writes:
> >>
> >> > Hi! I don't understand what about the "reference.docx", but in my 
> folder 
> >> > where I have the .md file I only have another .pdf file. 
> >> >
> >> > The command I use is: pandoc pxdxcomp.md -o pxdxcomp.docx
> >> > El jueves, 27 de mayo de 2021 a las 14:04:36 UTC-5, John MacFarlane 
> >> > escribió:
> >> >
> >> >> Also, please let us know the full command you are using to
> >> >> convert (including any options).
> >> >>
> >> >> John MacFarlane <j...-TVLZxgkOlNX2fBVCVOL8/A@public.gmane.org> writes:
> >> >>
> >> >> > Make sure you don't have a reference.docx in your user data
> >> >> > directory.
> >> >> >
> >> >> > Julio Vera <avenz...-Re5JQEeQqe8AvxtiuMwx3w@public.gmane.org> writes:
> >> >> >
> >> >> >> The latest one available in pandoc.org, I ran the script to 
> >> uninstall 
> >> >> it 
> >> >> >> and then downloaded it again for macOS. 
> >> >> >>
> >> >> >> I tested again with this file (prueba.md) that I created just to 
> see 
> >> if 
> >> >> it 
> >> >> >> woks with new files but I got the same result.
> >> >> >>
> >> >> >> [image: Captura de Pantalla 2021-05-27 a la(s) 12.54.14.png]
> >> >> >> However, when I convert the dxprevcovid19.md to .docx the table 
> >> there 
> >> >> >> renders fine. 
> >> >> >>
> >> >> >> El jueves, 27 de mayo de 2021 a las 12:49:09 UTC-5, John 
> MacFarlane 
> >> >> >> escribió:
> >> >> >>
> >> >> >>>
> >> >> >>> That's very strange -- it looks like it is using extremely narrow
> >> >> >>> columns. But I can't reproduce this with latest pandoc. It
> >> >> >>> looks fine. What version are you using?
> >> >> >>>
> >> >> >>> Julio Vera <avenz...-Re5JQEeQqe8AvxtiuMwx3w@public.gmane.org> writes:
> >> >> >>>
> >> >> >>> > [image: Captura de Pantalla 2021-05-27 a la(s) 12.27.20.png]
> >> >> >>> >
> >> >> >>> > Corrected it, but the tables are still not rendering. That's 
> how 
> >> I 
> >> >> see 
> >> >> >>> the 
> >> >> >>> > tables inside the docx just for that file (pxdxcomp.md), when 
> I 
> >> >> convert 
> >> >> >>> it 
> >> >> >>> > to pdf they render fine. 
> >> >> >>> >
> >> >> >>> > El jueves, 27 de mayo de 2021 a las 12:17:28 UTC-5, John 
> >> MacFarlane 
> >> >> >>> > escribió:
> >> >> >>> >
> >> >> >>> >>
> >> >> >>> >> Looks like you've got four ---- instead of three --- under the
> >> >> >>> >> YAML metadata block.
> >> >> >>> >>
> >> >> >>> >>
> >> >> >>> >> Julio Vera <avenz...-Re5JQEeQqe8AvxtiuMwx3w@public.gmane.org> writes:
> >> >> >>> >>
> >> >> >>> >> > Hi! 
> >> >> >>> >> >
> >> >> >>> >> > I attached 2 files. The one that I can't convert correctly 
> is 
> >> >> >>> >> pxdxcomp.md, 
> >> >> >>> >> > the other one (dxprevcovid) I tried to convert it and had 
> no 
> >> >> issue. 
> >> >> >>> The 
> >> >> >>> >> > language of my work is in Spanish, I hope it isn't an issue 
> >> here. 
> >> >> I 
> >> >> >>> >> tried 
> >> >> >>> >> > copying everything and pasting it inside a new file but 
> still 
> >> >> have 
> >> >> >>> the 
> >> >> >>> >> same 
> >> >> >>> >> > problem, also I uninstalled and installed pandoc.
> >> >> >>> >> >
> >> >> >>> >> > El jueves, 27 de mayo de 2021 a las 12:00:09 UTC-5, John 
> >> >> MacFarlane 
> >> >> >>> >> > escribió:
> >> >> >>> >> >
> >> >> >>> >> >>
> >> >> >>> >> >> Not much we can do to help without seeing the input 
> markdown 
> >> >> file...
> >> >> >>> >> >>
> >> >> >>> >> >> Julio Vera <avenz...-Re5JQEeQqe8AvxtiuMwx3w@public.gmane.org> writes:
> >> >> >>> >> >>
> >> >> >>> >> >> > I usually just ran the following command:
> >> >> >>> >> >> >
> >> >> >>> >> >> > pandoc nameofile.md --citeproc -o nameofile.docx
> >> >> >>> >> >> >
> >> >> >>> >> >> > But today I was working with a particular .md file and 
> >> after I 
> >> >> >>> >> finished 
> >> >> >>> >> >> > with it I tried to convert it, but the title, date and 
> >> author 
> >> >> >>> >> parameters 
> >> >> >>> >> >> > that go inside the YAML block aren't converted, they 
> >> display 
> >> >> like 
> >> >> >>> >> this:
> >> >> >>> >> >> >
> >> >> >>> >> >> > title: title of the document
> >> >> >>> >> >> > author: myname
> >> >> >>> >> >> > date: today
> >> >> >>> >> >> >
> >> >> >>> >> >> > But just in that format, not like it used to do. And 
> also 
> >> the 
> >> >> >>> tables 
> >> >> >>> >> >> aren't 
> >> >> >>> >> >> > formatted, they and up in the docs like this:
> >> >> >>> >> >> >
> >> >> >>> >> >> > p t
> >> >> >>> >> >> > r 2
> >> >> >>> >> >> > 1 2
> >> >> >>> >> >> > 2 2
> >> >> >>> >> >> >
> >> >> >>> >> >> > Just to say an example. I don't know hat happened.
> >> >> >>> >> >> >
> >> >> >>> >> >> > -- 
> >> >> >>> >> >> > You received this message because you are subscribed to 
> the 
> >> >> Google 
> >> >> >>> >> >> Groups "pandoc-discuss" group.
> >> >> >>> >> >> > To unsubscribe from this group and stop receiving emails 
> >> from 
> >> >> it, 
> >> >> >>> >> send 
> >> >> >>> >> >> an email to pandoc-discus...-/JYPxA39Uh5TLH3MbocFF+G/Ez6ZCGd0@public.gmane.org
> >> >> >>> >> >> > To view this discussion on the web visit 
> >> >> >>> >> >> 
> >> >> >>> >> 
> >> >> >>> 
> >> >> 
> >> 
> https://groups.google.com/d/msgid/pandoc-discuss/1abeeca5-7362-441d-907a-08df53958b28n%40googlegroups.com
> >> >> >>> >> >> .
> >> >> >>> >> >>
> >> >> >>> >> >
> >> >> >>> >> > -- 
> >> >> >>> >> > You received this message because you are subscribed to the 
> >> >> Google 
> >> >> >>> >> Groups "pandoc-discuss" group.
> >> >> >>> >> > To unsubscribe from this group and stop receiving emails 
> from 
> >> it, 
> >> >> >>> send 
> >> >> >>> >> an email to pandoc-discus...-/JYPxA39Uh5TLH3MbocFF+G/Ez6ZCGd0@public.gmane.org
> >> >> >>> >> > To view this discussion on the web visit 
> >> >> >>> >> 
> >> >> >>> 
> >> >> 
> >> 
> https://groups.google.com/d/msgid/pandoc-discuss/eaeda4d3-c7f4-430f-b569-e2fee781b831n%40googlegroups.com
> >> >> >>> >> .
> >> >> >>> >> > ---
> >> >> >>> >> > title: Diagnóstico situacional sobre la prevalencia de 
> >> SARS-COV-2 
> >> >> en 
> >> >> >>> >> perros, gatos y hurones de propietarios previamente 
> >> diagnósticados 
> >> >> con 
> >> >> >>> el 
> >> >> >>> >> virus.
> >> >> >>> >> > author: Julio Vera de León
> >> >> >>> >> > date: 25/Mayo/2021
> >> >> >>> >> > bibliography: proyecto.bib
> >> >> >>> >> > csl: vca.csl
> >> >> >>> >> > ---
> >> >> >>> >> >
> >> >> >>> >> > # Título
> >> >> >>> >> > **H. CONSEJO TÉCNICO DE LA FACULTAD**
> >> >> >>> >> > **DE MEDICINA VETERINARIA Y ZOOTECNIA**
> >> >> >>> >> >
> >> >> >>> >> > **Presente**
> >> >> >>> >> >
> >> >> >>> >> > Él que suscribe, **Julio Vera de León**, alumnos de la 
> >> Maestría 
> >> >> en 
> >> >> >>> >> Medicina Veterinaria y Zootecnia en el área de Salud Pública 
> y 
> >> >> Medicina 
> >> >> >>> >> Preventiva, con número de cuenta 52101425-4. Pone a su 
> >> >> consideración el 
> >> >> >>> >> siguiente tema para diagnóstico de situación:
> >> >> >>> >> >
> >> >> >>> >> > **Diagnóstico situacional sobre la prevalencia de 
> SARS-COV-2 
> >> en 
> >> >> >>> perros, 
> >> >> >>> >> gatos y hurones de propietarios previamente diagnósticados 
> con 
> >> el 
> >> >> >>> virus.**
> >> >> >>> >> >
> >> >> >>> >> > Que será realizado en el **Departamento de Medicina 
> Preventiva 
> >> y 
> >> >> >>> Salud 
> >> >> >>> >> Pública de la Facultad de Medicina Veterinaria y Zootecnia de 
> la 
> >> >> UNAM** 
> >> >> >>> y 
> >> >> >>> >> que pertenece al campo de profundización profesional: 
> **Medicina 
> >> >> >>> Preventiva 
> >> >> >>> >> y Salud Pública**. Bajo la asesoría del comité tutor 
> conformado 
> >> por 
> >> >> el 
> >> >> >>> >> **Dr. MSP Juan Ramón Ayala Torres**, la **MCV. Patricia Mora 
> >> >> Medina** y 
> >> >> >>> el 
> >> >> >>> >> **MCV. Jorge Francisco Monroy López**
> >> >> >>> >> >
> >> >> >>> >> > # Introducción
> >> >> >>> >> >
> >> >> >>> >> > El sustento de este diagnóstico de situación viene de que a 
> la 
> >> >> fecha 
> >> >> >>> es 
> >> >> >>> >> desconocido por el autor algún material bibliográfico o de 
> >> consulta 
> >> >> en 
> >> >> >>> el 
> >> >> >>> >> que se tengan datos referentes al número de animales que han 
> >> sido 
> >> >> >>> >> infectados por el síndrome respiratorio agudo severo 
> coronavirus 
> >> 2 
> >> >> >>> >> (SARS-COV-2). Esto a pesar de que la infección en los 
> animales 
> >> por 
> >> >> >>> >> SARS-COV-2 cumple los criterios de la OIE como enfermedad 
> >> >> emergente.[^1]
> >> >> >>> >> >
> >> >> >>> >> > Es relevante tener datos que nos permitan conocer la 
> >> prevalencia 
> >> >> del 
> >> >> >>> >> agente en los animales de compañía con los que mantenemos una 
> >> >> relación 
> >> >> >>> más 
> >> >> >>> >> cercana.
> >> >> >>> >> >
> >> >> >>> >> > [^1]: Enfermedad emergente por la OIE: La aparición de una 
> >> >> >>> enfermedad, 
> >> >> >>> >> infección o infestación nueva y que impacta en la sanidad 
> animal 
> >> o 
> >> >> la 
> >> >> >>> salud 
> >> >> >>> >> humana.
> >> >> >>> >> >
> >> >> >>> >> > A la fecha existen al menos 4 distintas instituciones en 
> >> América 
> >> >> que 
> >> >> >>> >> están realizando estudios de muestreo para conocer la 
> cantidad 
> >> de 
> >> >> >>> animales 
> >> >> >>> >> de compañia infectados por contacto con sus propietarios, las 
> >> >> cuales 
> >> >> >>> son:
> >> >> >>> >> >
> >> >> >>> >> > 1. [Ontario Veterinary College, University of Guelph](
> >> >> >>> >> https://ovc.uoguelph.ca)
> >> >> >>> >> > 2. [Cummings School of Veterinary Medicine at Tufts 
> >> University](
> >> >> >>> >> https://sites.tufts.edu/covers/)
> >> >> >>> >> > 3. [Texas A&M University, College of Veterinary Medicine & 
> >> >> Biomedical 
> >> >> >>> >> Sciences](
> >> https://vetmed.tamu.edu/hamer-lab/covid-19-pets-research/
> >> >> )
> >> >> >>> >> > 4. [University of Washington Center for One Health 
> Research](
> >> >> >>> >> 
> https://deohs.washington.edu/cohr/covid-19-and-pets-study-caps)
> >> >> >>> >> >
> >> >> >>> >> > La evidencia apunta a que la epidemia provocada por 
> SARS-COV-2 
> >> se 
> >> >> >>> >> mantiene principalmente por la transmisión de humanos hacia 
> >> otros 
> >> >> >>> humanos, 
> >> >> >>> >> por lo que en este estudio el enfoque será conocer la 
> cantidad 
> >> de 
> >> >> >>> animales 
> >> >> >>> >> que han sido infectados por sus propietarios, factores que 
> >> >> >>> contribuyeron a 
> >> >> >>> >> la infección, y conocer los tipos de casa en los que hubo más 
> >> >> riesgo de 
> >> >> >>> >> infección a las mascotas. Aunado a lo anterior, la OIE no 
> >> descarta 
> >> >> a 
> >> >> >>> los 
> >> >> >>> >> animales salvajes y domésticos como reservorios futuros de la 
> >> >> >>> enfermedad y 
> >> >> >>> >> que puedan representar un problema para la salud pública, por 
> lo 
> >> >> que 
> >> >> >>> >> sugiere el monitoreo cercano de las especies con las que más 
> >> >> >>> convivimos. De 
> >> >> >>> >> igual forma, la introducción constante del virus a nuevas 
> >> >> poblaciones 
> >> >> >>> >> animales puede llevar a mutaciones que puedan afectar la 
> sanidad 
> >> >> animal 
> >> >> >>> o 
> >> >> >>> >> salud humana.
> >> >> >>> >> >
> >> >> >>> >> > A la fecha la OIE cuenta con información referente a las 
> >> especies 
> >> >> de 
> >> >> >>> >> interés en este diagnóstico en cuánto a la susceptibilidad 
> que 
> >> >> tienen 
> >> >> >>> al 
> >> >> >>> >> virus, se pone en la siguiente tabla:[@OIE2021]
> >> >> >>> >> >
> >> >> >>> >> > | Especie | Tipo de infección | Susceptibilidad a la 
> infección 
> >> | 
> >> >> >>> Signos 
> >> >> >>> >> clínicos | Transmisión |
> >> >> >>> >> > | ------------------ | ---------------------- | 
> >> >> >>> >> ------------------------------ | -------------------------- | 
> >> >> >>> >> ----------------- |
> >> >> >>> >> > | Hurones | Natural y experimental | Alta | Sí (sólo en 
> >> algunos 
> >> >> >>> casos) | 
> >> >> >>> >> Sí, entre hurones |
> >> >> >>> >> > | Gatos (domésticos) | Natural y experimental | Alta | Sí 
> >> (sólo 
> >> >> en 
> >> >> >>> >> algunos casos) | Sí, entre gatos |
> >> >> >>> >> > | Perros | Natural y experimental | Baja | Sí (sólo en 
> algunos 
> >> >> casos) 
> >> >> >>> | 
> >> >> >>> >> No |
> >> >> >>> >> > Table: SARS-COV-2 en Hurones, perros y gatos (adaptado de 
> la 
> >> OIE)
> >> >> >>> >> >
> >> >> >>> >> > A pesar de que la información actual ha mencionado que la 
> >> >> epidemia se 
> >> >> >>> >> mantiene por medio de la transmisión humano-humano, no se 
> puede 
> >> >> >>> descartar 
> >> >> >>> >> como un componente de esta cadena de transmisión a los 
> animales 
> >> de 
> >> >> >>> >> compañia, aunque su papel de momento sea mucho menos 
> relevante. 
> >> De 
> >> >> ahí 
> >> >> >>> que 
> >> >> >>> >> una de las indicaciones que contempla la CDC sea la de 
> mantener 
> >> a 
> >> >> los 
> >> >> >>> >> animales separados junto con su propietario y reconoce el 
> riesgo 
> >> de 
> >> >> >>> >> transmisión desde la mascota es bajo. [@CDC2021]
> >> >> >>> >> >
> >> >> >>> >> > # Justificación
> >> >> >>> >> >
> >> >> >>> >> > La detección del material genético del virus de SARS-COV-2 
> en 
> >> >> perros 
> >> >> >>> y 
> >> >> >>> >> gatos se ha demostrado en animales con y sin signología, así 
> >> como 
> >> >> >>> también 
> >> >> >>> >> en el suero de mascotas que se han muestreado en zonas 
> >> afectadas, 
> >> >> por 
> >> >> >>> lo 
> >> >> >>> >> que la infección en estas especies está comprobada, y más 
> >> >> importante se 
> >> >> >>> ha 
> >> >> >>> >> comprobado que llegan a diseminar material viral con una 
> >> cantidad 
> >> >> >>> necesaria 
> >> >> >>> >> que ha demostrado ser capaz de infectar a otros animales con 
> los 
> >> >> que 
> >> >> >>> >> conviven. @Patterson2020
> >> >> >>> >> >
> >> >> >>> >> > En contraste con lo mencionado anteriormente, las especies 
> de 
> >> >> >>> producción 
> >> >> >>> >> como cerdos (*Sus scropha*) y aves (gallinas, patos y pavos) 
> han 
> >> >> >>> demostrado 
> >> >> >>> >> de nula a extremadamente baja susceptiblidad de infección de 
> >> manera 
> >> >> >>> >> experimental, además de que no se ha comprobado sean capaces 
> de 
> >> >> >>> transmitir 
> >> >> >>> >> la enfermedad. @Shi2020 De manera similar los bovinos (*Bos 
> >> >> taurus*) 
> >> >> >>> que se 
> >> >> >>> >> han inoculado experimentalmente con el agente viral han 
> >> demostrado 
> >> >> una 
> >> >> >>> >> susceptibilidad baja al agente y nula capacidad de 
> transmisión 
> >> del 
> >> >> >>> mismo. 
> >> >> >>> >> @Ulrich2020 
> >> >> >>> >> >
> >> >> >>> >> > Debido a que las especies usadas comúnmente en la ganadería 
> no 
> >> >> han 
> >> >> >>> >> demostrado ser suceptibles al virus, se decide enfocar el 
> >> >> diagnístico 
> >> >> >>> de 
> >> >> >>> >> situación en perros, gatos y hurones. De estos tres es de 
> >> >> particular 
> >> >> >>> >> relevancia mencionar a los hurones domésticos (*Mustela 
> outorius 
> >> >> >>> furo*), ya 
> >> >> >>> >> que pertenecen a la familia *Mustelidae* y guardan una 
> relación 
> >> >> >>> taxonómica 
> >> >> >>> >> con los mustélidos usados en granjas como lo es el visón 
> >> americano 
> >> >> >>> >> (*Neovison vison*) y visón europeo (*Mustela lutreola*), 
> estos 
> >> >> últimos 
> >> >> >>> >> responsables del brote de SARS-COV-2 que llevó a la eutanasia 
> de 
> >> 17 
> >> >> >>> >> millones de visones.[^2] 
> >> >> >>> >> >
> >> >> >>> >> > Aunque los hurones domésticos frecuentemente se encuentran 
> >> >> separados 
> >> >> >>> de 
> >> >> >>> >> otros y no son capaces de mantener la propagación del virus 
> de 
> >> >> manera 
> >> >> >>> >> estable @Gortazar2021, el gobierno del Reino Unido ha emitido 
> >> una 
> >> >> guía 
> >> >> >>> >> especial para los dueños de estos animales debido al riesgo 
> que 
> >> >> pueden 
> >> >> >>> >> representar [^3]. 
> >> >> >>> >> >
> >> >> >>> >> > [^2]: [¿Por qué Dinamarca sacrificó 17 millones de 
> visones?](
> >> >> >>> >> 
> >> >> >>> 
> >> >> 
> >> 
> https://www.nbcnews.com/news/animal-news/here-s-why-denmark-culled-17-million-minks-now-plans-n1249610
> >> >> >>> >> )
> >> >> >>> >> >
> >> >> >>> >> > [^3]: [Medidas preventivas en lo que respecta al SARS-COV-2 
> y 
> >> los 
> >> >> >>> >> hurones en el Reino Unido](
> >> >> >>> >> 
> >> http://apha.defra.gov.uk/documents/guidance-sars-cov-2-ferrets.pdf)
> >> >> >>> >> >
> >> >> >>> >> > Es así que en consideración al Código Sanitario para los 
> >> Animales 
> >> >> >>> >> Terrestres que contempla al SARS-COV-2 como una enfermedad 
> >> >> emergente y 
> >> >> >>> la 
> >> >> >>> >> falta de datos al respecto de la enfermedad en los animales 
> >> >> domésticos, 
> >> >> >>> es 
> >> >> >>> >> necesario realizar un diagnóstico de situación en nuestra 
> >> >> población. 
> >> >> >>> >> >
> >> >> >>> >> > # Referencias
> >> >> >>> >> > ---
> >> >> >>> >> > title: Ejercicio de pruebas diagnósticas complementarias
> >> >> >>> >> > author: Julio Vera de León
> >> >> >>> >> > date: 26/Mayo/2021
> >> >> >>> >> > ----
> >> >> >>> >> >
> >> >> >>> >> > # Primer prueba
> >> >> >>> >> >
> >> >> >>> >> > La primer prueba tamiz que se usa para brucelosis es la de 
> >> anillo 
> >> >> en 
> >> >> >>> >> leche. 
> >> >> >>> >> >
> >> >> >>> >> > Se hizo un diagnóstico con la prueba tamiz de anillo en 
> leche 
> >> >> para 
> >> >> >>> >> detectar a los hatos positivos a la enfermedad, estos hatos 
> >> cuentan 
> >> >> con 
> >> >> >>> >> 10.000 animales, los cuales fueron evaluados individualmente 
> >> para 
> >> >> >>> encontrar 
> >> >> >>> >> los positivos; a través de la prueba tamiz de rosa de bengala 
> la 
> >> >> cual 
> >> >> >>> tiene 
> >> >> >>> >> una sensibilidad del 95.2% y una especificidad del 98.5%.
> >> >> >>> >> >
> >> >> >>> >> > | Prueba | Positivos | Negativos | Total |
> >> >> >>> >> > | --------- | --------- | --------- | ----- |
> >> >> >>> >> > | Positivos | 286 | 145 | 431 |
> >> >> >>> >> > | Negativos | 14 | 9555 | 9569 |
> >> >> >>> >> > | Total | 300 | 9700 | 10000 |
> >> >> >>> >> >
> >> >> >>> >> > 1. Sanos: 9555
> >> >> >>> >> > 2. Enfermos postprueba: 286
> >> >> >>> >> > 3. Falsos positivos: 145
> >> >> >>> >> > 4. Falsos negativos: 14
> >> >> >>> >> > 5. Valor predictivo positivo: 66%
> >> >> >>> >> > 6. Valor predictivo negativo: 99%
> >> >> >>> >> > 7. Positivos a la prueba: 431 animales positivos, 
> incluyendo 
> >> >> falsos 
> >> >> >>> >> positivos. 
> >> >> >>> >> >
> >> >> >>> >> > Son muchos animales (431) que se van a eliminar incluyendo 
> los 
> >> >> 145 
> >> >> >>> >> falsos positivos, sacrificando 145 animales que no deberían 
> >> >> >>> sacrificarse, 
> >> >> >>> >> por lo que es necesario después de la prueba tamiz realizar 
> una 
> >> >> prueba 
> >> >> >>> >> mucho más especifica, por lo que se sugierte una prueba con 
> mas 
> >> >> >>> >> especificidad para bajar la cantidad de falsos positivos. 
> >> >> >>> >> >
> >> >> >>> >> > # Segunda prueba
> >> >> >>> >> >
> >> >> >>> >> > La siguiente prueba se hace en paralelo, la norma dice que 
> la 
> >> >> segunda 
> >> >> >>> >> prueba es la *prueba de ribanol*. Esta tiene una sensibilidad 
> >> del 
> >> >> 96.4% 
> >> >> >>> y 
> >> >> >>> >> especificidad de 98.7%
> >> >> >>> >> >
> >> >> >>> >> > Cuadro de 2x2: 
> >> >> >>> >> >
> >> >> >>> >> > | Prueba | Positivos | Negativos | Total |
> >> >> >>> >> > | --------- | --------- | --------- | ----- |
> >> >> >>> >> > | Positivos | 276 | 2 | 278 |
> >> >> >>> >> > | Negativos | 10 | 143 | 153 |
> >> >> >>> >> > | Total | 286 | 145 | 431 |
> >> >> >>> >> >
> >> >> >>> >> > 1. En que animales se aplicaría? Sobre el total de 
> positivos, 
> >> que 
> >> >> >>> sería 
> >> >> >>> >> 431
> >> >> >>> >> > 2. Verdaderos positivos: 276
> >> >> >>> >> > 3. Verdaderamente sanos: 143
> >> >> >>> >> > 4. Falsos positivos: 2
> >> >> >>> >> > 5. Falsos negativos: 10
> >> >> >>> >> > 6. Valor predicitvo positivo: 99% 
> >> >> >>> >> > 7. Valor predictivo negativo: 93%
> >> >> >>> >> >
> >> >> >>> >> > # Tercer prueba
> >> >> >>> >> >
> >> >> >>> >> > Al realizar un tercer diagnóstico con la prueba de fijación 
> >> del 
> >> >> >>> >> complemento (confirmatoria) con una sensibilidad del 97.5% y 
> >> >> >>> especificidad 
> >> >> >>> >> del 99%
> >> >> >>> >> >
> >> >> >>> >> > Cuadro 2 x2:
> >> >> >>> >> >
> >> >> >>> >> > | Prueba | Positivos | Negativos | Total |
> >> >> >>> >> > | --------- | --------- | --------- | ----- |
> >> >> >>> >> > | Positivos | 269 | 0 | 269 |
> >> >> >>> >> > | Negativos | 7 | 2 | 9 |
> >> >> >>> >> > | Total | 276 | 2 | 278 |
> >> >> >>> >> >
> >> >> >>> >> > 1. Animales falsos positivos que seran eliminados: 0
> >> >> >>> >> > 2. Animales falsos negativos que quedarán en el hato: 7
> >> >> >>> >> > 3. Valor predictivo positivo: 100%. Quiere decir que de los 
> >> >> animales 
> >> >> >>> a 
> >> >> >>> >> los que se les hace la prueba y están enfermos, el 100% 
> saldrán 
> >> con 
> >> >> un 
> >> >> >>> >> respultado positivo.
> >> >> >>> >> > 4. Valor predictivo negativo: 22%. Quiere decir de los 
> >> animales a 
> >> >> los 
> >> >> >>> >> que se les hace la prueba y están sanos, solamente el 22% 
> tiene 
> >> >> >>> >> probabilidad de estar realmente sano si salió negativo. 
> >> >> >>> >> > 
> >> >> >>> >> > # Después de las pruebas
> >> >> >>> >> >
> >> >> >>> >> > Al realizar un diagnóstico a los 6 meses de iniciado el 
> >> programa:
> >> >> >>> >> >
> >> >> >>> >> > 1. ¿Cuál es la prevalencia real final de la enfermedad en 
> la 
> >> >> cuenca 
> >> >> >>> >> lechera? 2.8% (278/10000)
> >> >> >>> >> > 2. La prevalencia real en el 3er cuadro: 99.3% 
> >> >> >>> >> > 3. ¿Cuál es la prevalencia aparente en el 3er cuadro? 2.7% 
> ()
> >> >> >>> >> > 4. Repercusiones de dejar a los animales falsos negativos 
> en 
> >> el 
> >> >> hato 
> >> >> >>> es 
> >> >> >>> >> que se quedan 7 animales con brucella, que pueden seguir 
> >> >> contagiando y 
> >> >> >>> >> prevalece la enfermedad. 
> >> >> >>> >> >
> >> >> >>> >> > El costo de la prueba da anillo en leche es absorbido por 
> el 
> >> >> gobierno 
> >> >> >>> >> como una ayuda a los productoras y un incentivo para 
> erradicar 
> >> esta 
> >> >> >>> >> zoonosis de tos animales. Sin embargo, el costo de las demás 
> >> >> pruebas es 
> >> >> >>> >> erogado por los productores:
> >> >> >>> >> >
> >> >> >>> >> > 1. Costo de diagnosticar a los 10,000 animales con rosa de 
> >> >> bengala 
> >> >> >>> >> (anillo en leche), si esta prueba cuesta $0.15 por 100 
> animales: 
> >> 15 
> >> >> >>> pesos
> >> >> >>> >> > 2. Costo de diagnosticar $1 por 100: serían $4.3
> >> >> >>> >> > 3. Costo de diagnosticar fijación por complemento $500 por 
> 100 
> >> >> >>> animales: 
> >> >> >>> >> $1390
> >> >> >>> >> > 4. Costo de eliminar a los animales positivos y falsos 
> >> positivos 
> >> >> >>> >> (separadamente), si una vaquilla de reemplazo cuesta $1,000 
> >> >> dolares. 
> >> >> >>> Costo 
> >> >> >>> >> de positivos: $278,000 dolares. 
> >> >> >>> >> > 5. Costo total de las 3 pruebas y de los animales a 
> >> sacrificar: 
> >> >> De 
> >> >> >>> las 3 
> >> >> >>> >> pruebas son $1409.3 pesos. 
> >> >> >>> >>
> >> >> >>> >
> >> >> >>> > -- 
> >> >> >>> > You received this message because you are subscribed to the 
> >> Google 
> >> >> >>> Groups "pandoc-discuss" group.
> >> >> >>> > To unsubscribe from this group and stop receiving emails from 
> it, 
> >> >> send 
> >> >> >>> an email to pandoc-discus...-/JYPxA39Uh5TLH3MbocFF+G/Ez6ZCGd0@public.gmane.org
> >> >> >>> > To view this discussion on the web visit 
> >> >> >>> 
> >> >> 
> >> 
> https://groups.google.com/d/msgid/pandoc-discuss/edd6a94c-a735-494d-88c5-bacabb6842b0n%40googlegroups.com
> >> >> >>> .
> >> >> >>>
> >> >> >>
> >> >> >> -- 
> >> >> >> You received this message because you are subscribed to the 
> Google 
> >> >> Groups "pandoc-discuss" group.
> >> >> >> To unsubscribe from this group and stop receiving emails from it, 
> >> send 
> >> >> an email to pandoc-discus...-/JYPxA39Uh5TLH3MbocFF+G/Ez6ZCGd0@public.gmane.org
> >> >> >> To view this discussion on the web visit 
> >> >> 
> >> 
> https://groups.google.com/d/msgid/pandoc-discuss/932560f4-7866-4fd4-90e7-4797e23fab20n%40googlegroups.com
> >> >> .
> >> >> >>
> >> >> >> Table tests to see if it works
> >> >> >>
> >> >> >> | Perros | Talla | Peso | Nombre |
> >> >> >> | ------ | ----- | ---- | ------ |
> >> >> >> | 23 | 5 | 6 | Chicu |
> >> >> >> | 24 | 2 | 4 | Fala |
> >> >> >> | 45 | 8 | 10 | Frty |
> >> >> >> Table: Perros 1
> >> >> >>
> >> >> >> Another table
> >> >> >>
> >> >> >> | Perros | Talla | Peso | Nombre |
> >> >> >> | ------ | ----- | ---- | ------ |
> >> >> >> | 23 | 5 | 6 | Chicu |
> >> >> >> | 24 | 2 | 4 | Fala |
> >> >> >> | 45 | 8 | 10 | Frty |
> >> >> >> Table: Perros 2
> >> >> >>
> >> >> >> And another table
> >> >> >>
> >> >> >> | Perros | Talla | Peso | Nombre |
> >> >> >> | ------ | ----- | ---- | ------ |
> >> >> >> | 23 | 5 | 6 | Chicu |
> >> >> >> | 24 | 2 | 4 | Fala |
> >> >> >> | 45 | 8 | 10 | Frty |
> >> >> >> Table: Perros 3
> >> >>
> >> >
> >> > -- 
> >> > You received this message because you are subscribed to the Google 
> >> Groups "pandoc-discuss" group.
> >> > To unsubscribe from this group and stop receiving emails from it, 
> send 
> >> an email to pandoc-discus...-/JYPxA39Uh5TLH3MbocFF+G/Ez6ZCGd0@public.gmane.org
> >> > To view this discussion on the web visit 
> >> 
> https://groups.google.com/d/msgid/pandoc-discuss/ba007430-af22-455f-a4a8-96011afe5dc3n%40googlegroups.com
> >> .
> >>
> >
> > -- 
> > You received this message because you are subscribed to the Google 
> Groups "pandoc-discuss" group.
> > To unsubscribe from this group and stop receiving emails from it, send 
> an email to pandoc-discus...-/JYPxA39Uh5TLH3MbocFF+G/Ez6ZCGd0@public.gmane.org
> > To view this discussion on the web visit 
> https://groups.google.com/d/msgid/pandoc-discuss/74450a6b-43ad-4780-90d6-80f51c203f1fn%40googlegroups.com
> .
>

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