There's a closed pull request on the void-packages repository

python3-setuptools: update to 52.0.0.
https://github.com/void-linux/void-packages/pull/28261

Description:
This release drops `easy_install`, which will cause hard failures when building python-module or python3-module templates that do not specify all of their setup_requires dependencies in `hostmakedepends`. This is a good thing; before, setuptools would fetch setup dependencies on its own, negatively impacting the reproducibility of package builds.

Still, I am going to run through rebuilds of some (most? all?) of the `python3-*` packages to check for build-time breakage.