There is an updated pull request by freshprince against master on the void-packages repository

https://github.com/freshprince/void-packages synapse-1.49.2
https://github.com/void-linux/void-packages/pull/34676

synapse: minor changes.
Don't patch sample config.

Make run script configurable so that admin can change path to config file and set locale if necessary.

Create /etc/synapse again.

~Log to daemon.notice.~ Logging daemon is not really necessary for this.

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A patch file from https://github.com/void-linux/void-packages/pull/34676.patch is attached