Could you provide the output or an error message?
For me its working with all installed kernel versions:

Building DKMS module 'virtualbox-ose-5.0.2' for kernel-4.0.9_1... done.
Installing DKMS module 'virtualbox-ose-5.0.2' for kernel-4.0.9_1... done.
Building DKMS module 'virtualbox-ose-5.0.2' for kernel-4.1.3_1... done.
Installing DKMS module 'virtualbox-ose-5.0.2' for kernel-4.1.3_1... done.
Building DKMS module 'virtualbox-ose-5.0.2' for kernel-4.1.4_1... done.
Installing DKMS module 'virtualbox-ose-5.0.2' for kernel-4.1.4_1... done.
Building DKMS module 'virtualbox-ose-5.0.2' for kernel-4.1.5_1... done.
Installing DKMS module 'virtualbox-ose-5.0.2' for kernel-4.1.5_1... done.
Building DKMS module 'virtualbox-ose-5.0.2' for kernel-4.1.6_1... done.
Installing DKMS module 'virtualbox-ose-5.0.2' for kernel-4.1.6_1... done.

Am Montag, 24. August 2015 14:26:57 UTC+2 schrieb Frankie Wild:

 Virtualbox ain't working for quite some time now. Last time it worked was when I booted with 3.19.8.1. 

Currently on up to date  4.1.6.1 force reconfigure fails against all kernels. 

xbps-query -l | grep header shows I have 3.19.8.1, 4.0.9.1 and 4.1.6.1 installed. Is this a conflict and shall I just leave the latest version in order to sort it out ?