I'm not sure if this is a issue on the system side or on the apllication side. Since the newest Android 12 Beta 4 Wireguard is establishing a connection but not data transfer is possible. A ping to the host is also not possible. There's an offical issue here at the Google Issuetracker: https://issuetracker.google.com/issues/196271165 This seems to be an issue with a lot of VPN apps . I don't know if it can be fixed on the application side.